GSTM1 and Alzheimer disease: Studies have queried whether certain genetic variants of GST might be risk agents for AD [40] and identified that the GSTM1*0 (homozygous deletion) and GSTP Ile105Val SNP (rs1695) genotypes are associated with AD pathology, with the GSTT1*0 genotype (homozygous deletion) conferring an increased risk for AD in Asian populations only [41,42,43].