By causing cell divisions, increasing cell motility, and stimulating the expression of genes including vascular endothelial growth factor (VEGF), hypoxia-inducible factors (HIF-1), vimentin (VIM), and REL proto-oncogene, NF-kB subunit (REL), Ang1-9 appears to have pro-cancer effects. The gene discussed is NFKB1; the disease is cancer.