APP and neuroblastoma: To explore the effects of liensinine and neferine on intracellular Aβ toxicity, we used Aβ-induced neurotoxicity in APP695swe SH-SY5Y cells, which constructed by stably transfecting with the human Swedish APP mutation APP695 in SH-SY5Y human neuroblastoma cells, as in vitro Aβ cell model.