For example, it has been reported that in hepatocellular carcinoma, the expression levels of CDK1 was positively correlated with the infiltration levels of CD4+ T cells, CD8+ T cells, neutrophils, macrophages and dendritic cells, suggesting that this gene may be involved in the recruitment and regulation of infiltrating cells in the immune microenvironment [33]. This evidence concerns the gene CD8A and hepatocellular carcinoma.