Quantification of the data revealed that treatment of cells with cisplatin lead to a two- to threefold up-regulation of Fas in 833 K and SuSa cells and a less than twofold induction of Fas in GCT27 testis and RT112 and HT1376 bladder cancer cells, while no up-regulation was observed in the bladder cancer cell line MGH-U1 (Fig. 4C) supporting the notion that the death receptor pathway becomes also activated following cisplatin treatment in drug-sensitive testis tumor cells. Here, FAS is linked to urinary bladder carcinoma.