Among them, miRNAs (has-miR-3127-5p and has-miR-3184-5p), lncRNAs (AL356488.2 and AL645608.3) and TFs (NANOG and HEY1) as the key regulatory factors of PRM2, FSCN3 and TEKT2, were predicted significantly associated with male infertility. Here, TEKT2 is linked to male infertility.