Additionally, in crude OR analyses, SGLT-2 inhibitor exposure was associated with a higher genital infection risk in the following strata: females, CCI of 2, and baseline comorbidity of chronic lower respiratory disease, with crude ORs of 1.76 (p = 0.03), 3.13 (p = 0.02) and 2.35 (p = 0.03), respectively. The gene discussed is SLC5A2; the disease is lower respiratory tract disorder.