MTOR and metabolic dysfunction-associated steatohepatitis: Meanwhile, we also found that the AMPK-activated protein kinase (AMPK/mTOR) signaling pathway had a crucial role in the regulation of lipid metabolism mediated by HUC-MSCs or exosomes23, which could attenuate glycolipid metabolism dysfunction by activating AMPK expression24, thus contributing to ameliorating or reversing lipolysis or inflammation levels in OA/PA-treated hepatocytes or liver of NASH mice.