For example, the interaction between Twist and BRD4 plays roles in basal-like breast cancer, and this protein complex is required for WNT5A expression and malignant processes; the BET-specific inhibitors JQ1 and MS417 block both cancer cell invasion and tumorigenicity by targeting the interaction, thus representing a potential treatment for basal-like breast cancer [41]. This evidence concerns the gene DNER and breast cancer.