STRA8 and Infertility: Although our attempt to analyze the role of FIGNL1 in mouse oocytes failed due to insufficient excision of the Fignl1flox allele in oocytes by the Stra8-Cre transgene used in this study, a recent study by Yu and colleagues demonstrated the accumulation of RAD51 in not only Firrm/Flip cKO spermatocytes but also in oocytes with infertility in both male and female mice55, suggesting that the essential role of the FIGNL1-FIRRM complex in meiotic recombination is shared between males and females.