TP53 and neoplasm: Because cellular stress response pathways may have profound immunomodulatory functions in tumor cells (Ishimoto et al, 2011; Michaud et al, 2011; Senovilla et al, 2012; Duan et al, 2019; Li et al, 2019; Fox et al, 2020; Chen & Cubillos-Ruiz, 2021; Guo et al, 2021), we also wanted to evaluate whether APR-246 can impact the antigenicity of tumor cells even in the absence of p53.