SOX9 and colorectal carcinoma: Mining TCGA data, we found that SOX9 C-terminal truncating mutations were significantly associated with higher SOX9 RNA expression in both GC and CRC (GC: log2FoldChange 0.86; adjusted p value 9.8 × 10−3; CRC: log2FoldChange 0.73; adjusted p value 6.2 × 10−10) (Figure 1E), supporting previous reports that SOX9 truncating exon 3 mutations are associated with higher SOX9 protein expression.25