The frequency of TEAEs and drug-related AEs was higher in patients with CP-B cirrhosis (32.0% and 20.0%, respectively) compared with patients with CP-A cirrhosis (12.5% and 8.3%, respectively), with orthostatic intolerance being the most frequently reported drug-related AE (n = 1 each per CP-A 3 mg BID, CP-B 2 mg BID, and CP-B 3 mg BID). This evidence concerns the gene CPA1 and congenital primary aphakia.