Testosterone stimulates erythropoietin transcription, increases iron availability for erythropoiesis by suppressing hepcidin transcription, increases the numbers of common myeloid progenitors, and improves red cell survival.15,26,27,28,29 Testosterone corrects anemia of inflammation by improving iron availability and by promoting maturation of erythroid precursors.28 The gene discussed is EPO; the disease is anemia.