EDN1 and type 2 diabetes mellitus: A recent study investigating vascular endothelial function and pulmonary function in patients with type 2 diabetes, found a strong correlation between DLCO and vascular endothelial function parameters (nitric oxide, r = 0.797, endothelin-1, r = – 0.787 and flow mediated dilatation, r = 0.700) (3).