DRAM1 and colorectal carcinoma: As seen from the Fig. 5i, the expression of DRAM1, NBR1, ATG7, and MAP1LC3A genes increased gradually in both the CRC + Fn group and CRC + Fn + Cys group, especially DRAM1, NBR1, and MAP1LC3A, which showed a significant increase in expression in CRC + Fn + Cys group when compared with the control group.