The relative abundance of the top 10 bacteria at the genus level in the mouse intestine (Fig. 6e) was compared and clustered between groups, and it was found that the bacteria were specific between each group, e.g., Escherichia_Shigella in the CRC group was more abundant than the other groups, and Lachnospiraceae_NK4A136_group in the Fn group was more abundant than the other groups, but the fungi were not specific between each group. This evidence concerns the gene FN1 and colorectal carcinoma.