The levels of relevant target gene expression (e.g., CYP1A1 and CYP2B6) increased with the aberrant activation of AHR or CAR, which can lead to lipid metabolism disorders, reduced levels of anti-inflammatory elements [38], and a significant decrease in levels of antioxidant enzyme markers (glutathione and catalase) [9]. Here, NR1I3 is linked to Disorder of lipid metabolism.