(2) Overexpression of cancer genes, such as FAM20C, PDGFRB, LAMB2, PSME2, CAD, ANXA3, MBNL1, EWSR1, RPL23A, NPNT, and SERPINH1, is consistent with the reports that ZEN promotes cancer occurrence, which will lead to disruption of the oocyte metabolic system [29,30,31,32,33,34,35,36,37,38,39]. This evidence concerns the gene ANXA3 and cancer.