Small PA “doses” throughout the day to break sitting can attenuate postprandial glucose and insulin levels, particularly in individuals with insulin resistance [14], in which regular aerobic exercise improves glycemic control in adults with type 2 diabetes, with a shorter daily time of hyperglycemia and a reduction of 0.5–0.7% global glycemia (as measured by HbA1c) [14]. This evidence concerns the gene INS and Insulin resistance.