One of the key factors when verifying glycemic control actions, especially those related to adequate levels of PA in T1DM and T2DM patients and taking into account the context of COVID-19, is that the imbalance of metabolic parameters (blood glucose, HbA1c, insulin, triglycerides, LDL, etc.)is directly related to the severity of COVID-19 if these individuals are infected by the SARS-CoV-2 virus [2,7,8]. The gene discussed is INS; the disease is type 1 diabetes mellitus.