As is the case with other developmental genes, FOXF1, e.g., [13,14,15] and FENDRR, e.g., [16,17] are also involved in the pathogenesis of cancer; depending, e.g., on tissue context, they can function as tumor suppressors or oncogenes (FOXF1 as a transcription factor; FENDRR as a molecular sponge of miRNAs or scaffold/carrier for chromatin/mRNA modifying complexes). The gene discussed is FOXF1; the disease is cancer.