SOX2 and squamous cell carcinoma: Schröck et al. [32] assessed SOX2 gene amplification and protein expression using fluorescence in situ hybridization and immunohistochemistry, respectively, in 159 sinonasal tumors, including 59 squamous cell carcinomas (SCCs), 18 SNUCs, 10 carcinomas associated with an inverted papilloma (INVCs), 19 adenocarcinomas, and 13 adenoid cystic carcinomas.