Cox regression analysis confirmed that TROP-2 expression and tumor invasion were two independent prognostic factors for gallbladder cancer in univariable (RR = 0.259, 95% CI 0.163–0.412, p = 0.0000) and multivariable analysis (RR = 0.463, 95% CI 0.274–0.782, p = 0.004) [20]. Here, TACSTD2 is linked to neoplasm.