BRCA1 and cancer: The rate of RRSO for NL BRCA1/2 PV carrier females was 75.7%, higher than reported by other clinics worldwide (36.7–71.8%) [32], and is attributed to specialist assessment, strengthened by a dedicated cancer genetics clinic run by the gynecologic oncology team, close relationships within the medical community, personalized menopause care, and outreach and educational programming led by local OC advocacy groups.