Anti-cancer effects of O. majorana ethanol extract have been described in various human cancer cell lines and are based on the suppression of colony growth, cell viability, and induction of mitotic arrest, DNA damage, triggering of the abortive autophagy, and activation of a caspase-3- and 7-dependent extrinsic apoptotic pathway [11,12,13]. Here, CASP3 is linked to cancer.