FADS2 and Cowden disease: As for IBD subtypes, the FADS2 gene showed a stronger effect on lowering the risk of CD (ORs (95% CI) were 0.78 (0.71–0.86) for total omega-3, 0.38 (0.25–0.57) for EPA, and 0.35 (0.23–0.55) for DHA) but was absent for UC.