HCRT and Anxiety: These peptides, which are well conserved in zebrafish [192,193,194], as demonstrated for Hcrt [195], Mch [196], Gal [197,198], Enk [199] and Dyn [200], are shown to have a natural functional relationship with a number of behaviors, including locomotor activity [201,202], anxiety [203,204], the sleep/wake cycle [205,206], and consummatory behavior [146,207].