PGRMC1 and glioblastoma: Our study aimed to characterize: (1) the association between PGRMC1 expression and the clinical outcome of GBM patients, (2) the effect of PGRMC1 on the intrinsic functions of the GBM cells, (3) the effect of PGRMC1 on the response of GBM cells to treatment with TMZ and ferroptosis inducers, and (4) the effect of PGRMC1 on GBM-induced modulation of neutrophil biology.