Caire et al. utilized synovial organoids from RA patients in order to identify the greater transcriptional activity of the coactivators YAP/TAZ (where TAZ is WW-domain-containing transcription regulator 1) in rheumatoid cells in comparison to the controls, suggesting YAP/TAZ as possible target for treatment. The gene discussed is WWTR1; the disease is rheumatoid arthritis.