MYC and cancer: The results of gene set enrichment analysis showed a total of 17 common gene sets with positive correlations with high-grade meningioma, including MYC target variant 1 (M5926), a hallmark gene set of proliferation that has been found to be most prominent in cancers with a maximum consolidated normalized enrichment score (NES), followed by E2F targets and the cell cycle G2/M checkpoint, which also came under the proliferation category of the hallmark gene set (Figure 2B).