Mutations in different genes have been shown to cause monogenic dyslipidemia, including LDLRAP1 mutations that are involved in autosomal recessive hypercholesterolemia, ABCG5/ABCG8, involved in sitosterolemia, or LMF1, which is associated with familial chylomicronemia syndrome [56]. This evidence concerns the gene ABCG8 and metabolic syndrome.