However, a long-living (18 years) strictly herbivorous rodent (Octodon degus) was found in the upper mountainous regions of Chile [140], which does spontaneously develop cognitive decline with the altered cholinergic transmission, hyperphosphorylated-tau, β-amyloid plaques, NFT, and neuroinflammation in the brain [141,142]. Here, MAPT is linked to Mental deterioration.