Most recently, a reduction in both mRNA and protein expression for putative LESC markers, K15, ∆Np63α and glycoprotein hormone alpha-2 (GPHA2) (Figure 1) was detected in the basal limbal epithelia of corneas obtained from streptozotocin (STZ)-induced T1D mice [67]. This evidence concerns the gene GPHA2 and type 1 diabetes mellitus.