PLK1 and cancer: We obtained and displayed 20 proteins interacting with CEP55 from the STRING web tool, and the associated protein networks are shown in Figure 6A. In addition, we analyzed the top 100 genes associated with CEP55 expression in 33 cancers of TCGA by GEPIA2, of which the top 5 were cyclin-A (CCNA2), cyclin dependent kinase 1 (CDK1), kinesin family member 11 (KIF11), marker of proliferation Ki-67 (MKI67), and Polo-like kinase 1 (PLK1), which were significantly positively associated with CEP55 (Figure 6B).