SLC9A3 and Sepsis: Schmidt et al. [191] conducted a study that demonstrated a significant decrease in the expression of various renal transport proteins, including Na+/H+ exchanger 3 (NHE3), Na+/K+-ATPase, renal outer medullary K+ channel (ROMK), ENaC, Na+–K+–2Cl−-cotransporter 2 (NKCC2), Na+–Cl− cotransporter (NCC), and kidney specific chloride channel -1 and -2 (CLCK-1 and -2), as well as Barttin, in an in vivo model of rat sepsis induced via the intraperitoneal injection of liposaccharide (LPS).