Genetic changes in the FKRP gene lead to the development of a wide spectrum of pathologies, ranging from severe diseases such as Congenital Muscular Dystrophy Type 1C (MDC1C), Walker–Warburg Syndrome (WWS), and Muscle–Eye–Brain diseases (MEB) to mild muscular dystrophies such as Limb-Girdle Muscular Dystrophy Type R9 (LGMDR9) [9,10,11]. The gene discussed is FKRP; the disease is muscular dystrophy-dystroglycanopathy, type A.