MYCN and neuroblastoma: As summarized in Table 1, the enrolled patients showed the typical characteristics of HR-NB: a median of 42 months old at diagnosis (range 30–75 months), 86% (6/7) with an adrenal gland tumor, 29% (2/7) with a MYCN-amplified tumor, 71% (5/7) with BM metastasis at diagnosis, and 86% (6/7) with INSS stage 4.