Our pathway analysis revealed that the dysregulated microRNAs were associated with critical pathways involved in cell death (Caspases, FASN), fibrosis (TGF, Col1, SMADs and MMPs) inflammation (IL6, TNF and PPARG), steatosis and fatty acid metabolism (ABHD family, ACOX1, ACOX3, HMGCR and LCLAT1), specifically regulating triglyceride metabolism in the hepatic lipid droplets (PNPLA2 (aka ATGL), ABHD5 and PNPLA3). The gene discussed is HMGCR; the disease is steatosis.