PPARG and diabetes mellitus: Among them, the inhibitors of α-glucosidase, aldose reductase (ALR2), diacylglycerol acyltransferase (DGAT), protein tyrosine phosphatase localized to mitochondrion 1 (PTPM1), peroxisome proliferator-activated receptor gamma (PPARγ), DRAK2 and advanced glycation end products (AGE) are excessively studied enzymatic mechanisms of diabetes [42].