Treatment with thiopurines results in a higher risk of NMSC.16 Treatment with TNF-α inhibitors might be associated with melanoma though recent reviews do not support this association.3,17 In the IBSEN cohort, 1 patient with NMSC was prescribed thiopurines, 1 patient TNF-α inhibitor only, and 2 patients were prescribed both. This evidence concerns the gene TNF and melanoma.