Factors including age at diagnosis; BMI; disease duration; MRI characteristics such as macroadenoma occurrence rate, cavernous sinus invasion, and compression of the optic chiasm; having complications; decreased libido; endocrine features GH; IGF-1 levels; serum prolactin levels; the pathology factor of prolactin secretin tumors; and recovery from acromegaly were compared. This evidence concerns the gene GH1 and acromegaly.