Deficiencies in other pituitary target organ axes included a 6.7% (17/252) deficiency rate in the adrenocorticotropic hormone (ACTH)–cortisol axis and a 3.2% (8/252) deficiency rate in the thyroid-stimulating hormone (TSH)–thyroid axis. Here, POMC is linked to hyperinsulinemic hypoglycemia, familial, 4.