This population has a greater prevalence of BRCA1 and BRCA2 gene mutations, which increases the chance of getting breast and ovarian cancer and reported elevated carrier frequency of 0.9% in the Ashkenazi Jewish population, a specific BRCA1 mutation known as 185delAG is also occasionally seen in non-Jewish patients with a distinct haplotype (105). The gene discussed is BRCA2; the disease is ovarian carcinoma.