Hedgehog pathway inhibitors (e.g., Vismodegib in basal cell carcinoma)STAT3 inhibitors (e.g., Napabucasin in pancreatic cancer). Notch signalling pathway inhibitors in breast cancer.Hedgehog pathway inhibitors in medulloblastoma (207, 212–214). The gene discussed is STAT3; the disease is pancreatic neoplasm.