In addition, the situation in CC patients was more serious than in CIN patients [9].According to the studies, the more severe the disease was, the more visible the changes in the four categories of CD4 + T cells were.The cell percentages were all connected to the stage of the tumor, the extent of tumor vaso invasion, and the presence of lymph nodemetastases. The gene discussed is CD4; the disease is cervical squamous intraepithelial neoplasia.