The results of Yulan Zhen et al. showed that the treatment of HCC cells with NaHS significantly increased the expression levels of p-STAT3 and STAT3 mRNA, which led to the increased expression levels of COX-2 and COX-2 mRNA, the increased VEGF level, the reduced cleaved caspase-3 level, the increased viability and migration of HCC cells and the reduction of HCC cells apoptosis. This evidence concerns the gene CASP3 and hepatocellular carcinoma.