At the 3rd FU after LVAD implantation, CD4+ T cells of obese patients (62.4 ± 9.0%) remained above this range and significantly differed in comparison to pre-obese patients (52.7 ± 10.0%, ppre-obesity vs. obesity = 0.05) (Figure 1A). This evidence concerns the gene CD4 and obesity due to melanocortin 4 receptor deficiency.