CD47 and medulloblastoma: (116) tested a humanized anti-CD47 antibody, Hu5F9-G4, on five types of aggressive pediatric brain tumors (group 3 medulloblastoma (primary and metastatic), ATRT, PNET, pediatric glioblastoma, and DIPG) in patient-derived orthotopic xenograft models, and efficacy was demonstrated in both in vivo and in vitro.