In the months following the announcement of the first cases of SARS-CoV-2 in China, angiotensin I converting enzyme 2 (ACE2) was identified as the receptor for this new virus (13) It was subsequently demonstrated that, in addition to serving as attachment receptor to the virus, the ACE2 molecule plays a crucial role in the pathophysiology of COVID-19 (14, 15). This evidence concerns the gene ACE2 and COVID-19.