IGHE and Alzheimer disease: We previously reported that mRNA levels coding for FcεRIα, the IgE-binding sub-unit of the high-affinity receptor for IgE reflected local MC numbers in this animal model of AD [18], yet were not significantly increased after OVA treatment, neither was MC degranulation (Figure 2b,d) compared to saline controls (Figure 2a,c) and in contrast to female mice [18].