The cardiac biomarker NT-pro-BNP (mean ± SD) calculated by the Mann-Whitney test was found to be higher in non-survivors (503.24 ± 269.3) as compared to survivors (503.24 ± 269.3) (p-value < 0.0001), indicating an increase in cardiac enzyme showing the myocardium involvement in sepsis and septic shock [8]. The gene discussed is NPPB; the disease is Shock.