UMOD and autosomal dominant medullary cystic kidney disease with or without hyperuricemia: These cells (hereafter referred to as UMOD‐GFP cells) recapitulated the main biochemical features of ADTKD‐UMOD, including the formation of HMW (~above 250 kDa) aggregates (Fig 7A) that were resolved by treatment with DTT (Appendix Fig S12A), accumulation of EndoH‐sensitive premature uromodulin (Fig 7B) and reduced uromodulin secretion (Fig 7C).